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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HEATR1
All Species:
22.73
Human Site:
S805
Identified Species:
38.46
UniProt:
Q9H583
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H583
NP_060542.4
2144
242370
S805
Y
A
L
K
A
P
K
S
F
P
K
G
D
I
W
Chimpanzee
Pan troglodytes
XP_001156974
2144
242420
S805
Y
A
L
K
A
P
K
S
F
P
K
G
D
I
W
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536334
2141
242568
S805
H
A
L
K
A
P
K
S
F
P
K
D
D
I
W
Cat
Felis silvestris
Mouse
Mus musculus
NP_659084
2143
242053
S805
F
A
M
K
A
P
K
S
F
P
T
G
A
M
W
Rat
Rattus norvegicus
NP_001101888
2143
241191
S805
F
A
L
K
A
P
K
S
F
P
T
G
A
M
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422958
2155
244590
S807
N
D
L
K
P
P
S
S
F
P
K
E
E
T
W
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q7SY48
2159
242032
S797
T
T
L
K
C
P
D
S
T
F
K
G
E
P
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VM75
2096
237201
A796
R
L
L
E
I
I
C
A
Q
V
F
S
E
K
A
Honey Bee
Apis mellifera
XP_393800
2028
231830
M765
L
I
L
R
L
L
E
M
F
F
E
G
I
E
N
Nematode Worm
Caenorhab. elegans
Q23495
1650
185210
N446
K
D
K
K
T
L
K
N
V
L
K
E
Y
Q
I
Sea Urchin
Strong. purpuratus
XP_794611
1635
181917
A431
R
D
L
R
E
K
I
A
P
V
V
Q
S
L
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C8Z4
2001
224001
L763
S
K
S
N
C
Q
E
L
L
Y
Q
L
L
D
T
Baker's Yeast
Sacchar. cerevisiae
P42945
1769
200063
P565
V
N
I
F
T
L
V
P
C
L
I
C
A
L
R
Red Bread Mold
Neurospora crassa
Q7RZM8
1788
196873
T584
L
K
D
E
E
F
A
T
L
D
F
Q
A
V
V
Conservation
Percent
Protein Identity:
100
99.5
N.A.
89.7
N.A.
83.8
84.9
N.A.
N.A.
65.5
N.A.
54.5
N.A.
28.6
30.5
21.1
24.4
Protein Similarity:
100
99.8
N.A.
95
N.A.
92.1
92.7
N.A.
N.A.
80.5
N.A.
73
N.A.
49.4
50.8
38.9
43.2
P-Site Identity:
100
100
N.A.
86.6
N.A.
66.6
73.3
N.A.
N.A.
53.3
N.A.
46.6
N.A.
6.6
20
20
6.6
P-Site Similarity:
100
100
N.A.
93.3
N.A.
86.6
86.6
N.A.
N.A.
60
N.A.
53.3
N.A.
26.6
40
26.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.4
21.2
23
Protein Similarity:
N.A.
N.A.
N.A.
43.4
40.2
42.2
P-Site Identity:
N.A.
N.A.
N.A.
0
0
0
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
13.3
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
36
0
0
36
0
8
15
0
0
0
0
29
0
8
% A
% Cys:
0
0
0
0
15
0
8
0
8
0
0
8
0
0
0
% C
% Asp:
0
22
8
0
0
0
8
0
0
8
0
8
22
8
0
% D
% Glu:
0
0
0
15
15
0
15
0
0
0
8
15
22
8
8
% E
% Phe:
15
0
0
8
0
8
0
0
50
15
15
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
43
0
0
0
% G
% His:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
8
0
8
8
8
0
0
0
8
0
8
22
8
% I
% Lys:
8
15
8
58
0
8
43
0
0
0
43
0
0
8
0
% K
% Leu:
15
8
65
0
8
22
0
8
15
15
0
8
8
15
0
% L
% Met:
0
0
8
0
0
0
0
8
0
0
0
0
0
15
0
% M
% Asn:
8
8
0
8
0
0
0
8
0
0
0
0
0
0
8
% N
% Pro:
0
0
0
0
8
50
0
8
8
43
0
0
0
8
0
% P
% Gln:
0
0
0
0
0
8
0
0
8
0
8
15
0
8
0
% Q
% Arg:
15
0
0
15
0
0
0
0
0
0
0
0
0
0
8
% R
% Ser:
8
0
8
0
0
0
8
50
0
0
0
8
8
0
0
% S
% Thr:
8
8
0
0
15
0
0
8
8
0
15
0
0
8
8
% T
% Val:
8
0
0
0
0
0
8
0
8
15
8
0
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
50
% W
% Tyr:
15
0
0
0
0
0
0
0
0
8
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _